Alzheimer's disease, the leading cause of dementia, is a gradual erosion of memory, cognitive ability, and personality. Today, an estimated 5 million Americans and one in ten people over the age of 65 have the disease. As our society ages, it could affect as many as 16 million people in the United States by 2050.
There is no cure, but medications can alleviate symptoms. Emory scientists are taking a variety of approaches in attacking this devastating condition. Those approaches range from studying the basic chemistry of aggregated proteins to advanced imaging techniques, which are used to visualize changes in the brain as Alzheimer's disease progresses. With recent advances in imaging, genetics and biochemistry, it is an exciting time for the Alzheimer's field.
Emory researchers are focusing on key molecules that regulate amyloid, the protein that builds up in characteristic plaques in Alzheimer's patients' brains. These could be targets for future medications that could alter the course of the disease. They also are developing techniques for early diagnosis, in order to identify patients when treatment could be more effective.